JEEP 2009, 00019 (2009)
DOI: 10.1051/jeep/200900019

Hydration and Dehydration of the Pure Enantiomer and the Racemic of Phencyphos

F. Querniard¹, M. Leeman², Y. Cartigny¹, R.M. Kellogg², E. Vlieg³ and G. Coquerel<sup>1

1</sup>  SMS laboratory, University of Rouen, rue Lucien Tesnière, Mont Saint Aignan, 76821, France
²  Syncom BV, Kadijk 3, Groningen, 9747AT, The Netherlands
³  Solid State Chemistry, Institute for Molecules and Materials, Radboud University, Heyendaalseweg 135, Nijmegen, 6525 AJ, The Netherlands

Florian.querniard@etu.univ-rouen.fr

Published online: 4 December 2009

Abstract
This study is devoted to the understanding of phencyphos hydration/dehydration behaviour. Phencyphos is a resolving agent used in the so-called Dutch resolution. Batches of phencyphos contain various amounts of water (from 0 to 1 equivalent of water) evolving over time, inducing wrong dosages. Phase diagrams between phencyphos, water and methanol or ethanol were determined. Then, solid phases were characterized and compared with the means of X-ray Powder Diffraction, InfraRed spectroscopy, Differential Scanning Calorimetry and Dynamic Vapour Sorption. All these experiments have led to reliable conversion methods and storage conditions.

Key words: Phencyphos -- Hydration -- Dehydration, Phase diagrams


© Owned by the authors, published by EDP Sciences 2009